Non-insulin-dependent diabetes mellitus

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Non-insulin-dependent diabetes mellitus.

Non-insulin-dependent diabetes mellitus (NIDDM) occurs predominantly after the age of 50 years but is not easy to distinguish from late onset insulin-dependent diabetes. It is likely that misclassification is rare in a Caucasian population. Whilst NIDDM is widely believed to be genetically determined, recent epidemiological observations have consistently revealed statistical associations betwee...

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Insulin-Dependent Diabetes Mellitus

From the School of Nursing (Drs Boehm, Schlenk, and Ronis and Ms Powers) and the Michigan Diabetes Research and Training Center, School of Medicine (Ms Funnell), University of Michigan, and the Department of Veteran’s Affairs (Dr Ronis), Ann Arbor, Michigan. Correspondence to Susan Boehm, PhD, Associate Professor and Dean, Student Affairs, The University of Michigan, School of Nursing, 400 Nort...

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Optimum Insulin Therapy in Non-insulin-dependent Diabetes Mellitus *

However, it has also been recognized that the treatment of NIDDM patients frequently is inadequate even in those patients who should achieve the target range. In a recent population based cohort the median of glycosylated haemoglobin was 10.2% in NIDDM patients treated with diet or oral hypoglycemic agents (OHA) and 11.8% in NIDDM patients who used insulin. In a 5 year follow-up study of NIDDM ...

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A variant insulin promoter in non-insulin-dependent diabetes mellitus.

To test the hypothesis that alterations in regulatory regions of the insulin gene occur in a subset of patients with non-insulin-dependent diabetes mellitus (NIDDM), the promoter region was studied by polymerase chain reaction (PCR) amplification directly from genomic DNA, followed by high-resolution polyacrylamide gel electrophoresis under nondenaturing conditions. By using this method a previ...

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Insulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus

Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...

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ژورنال

عنوان ژورنال: British Medical Bulletin

سال: 1997

ISSN: 0007-1420,1471-8391

DOI: 10.1093/oxfordjournals.bmb.a011594